Item — HN Reader

by KasianFranks·10y ago·view on hn ↗

AI applied to understanding the hidden relationships linking epigentics and extending human lifespan via algorithmically engineered diet, nutrition and longevity genomics:

The precedent:

Laura Deming: Making a business out of fighting the ills of aging

https://www.youtube.com/watch?v=jbYgza4NNk8

Cynthia Kenyon: Experiments that hint of longer lives

(Cynthia now works at Google's Calico Labs)

https://www.youtube.com/watch?v=V48M5j-6zdE

Now connect this:

Nutrigenomics, Epigenetics, and Stress Tolerance

https://www.youtube.com/watch?v=qvNLNl7oJnM

Now combine with:

What is Epigenetics? with Nessa Carey

The last 10mins are very important, in particular minute 35:06

https://www.youtube.com/watch?v=9DAcJSAM_BA

Statistical modeling of biomedical corpora: mining the Caenorhabditis Genetic Center Bibliography for genes related to life span - Blei DM1, Franks K, Jordan MI, Mian IS. - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533868

Combining the worlds variants of pattern recogition, machine learning and AI with data associated to epigentic and standard genomic experiments and information, we should be able to discover hidden relationships that will enable advancement in extending human lifespan.

Revenue is something we'll need to focus on and that may come in the form of consumer applications that algorithmically engineer their epigenome with data from companies like 23andMe, Navigenics, Ubiome etc. connected to Nutrigenomics including plant compounds, phytochemicals mapped all the way to the consumer through foods connected to apps connected shopping and recipe experiences.

Finally connect to CRISPR and Gene Therapy

Jennifer Doudna, inventor of CRISPR: We can now edit our DNA. But let's do it wisely

http://www.ted.com/talks/jennifer_doudna_we_can_now_edit_our...

Include:

At some point we'll need to enter the Breakthrough Prize on longevity:

https://breakthroughprize.org/Prize/2

Along with collaborating with

The Buck Institute: http://thebuck.org Berkeley Lab: http://www.lbl.gov SENS: http://sens.org Calico Labs: http://calicolabs.com

Why biomedical superstars are signing on with Google

http://www.nature.com/news/why-biomedical-superstars-are-sig...

‘Your Genome Isn’t Really Secret,’ Says Google Ventures’s Bill Maris

http://www.bloomberg.com/news/articles/2015-10-20/-your-geno...