Yes and ignores the multi-device climate where the designs ultimately will live. Makes me think the pixel-perfect prototype is creating a bit of a fiction. Of course most good designers keep that in mind, but I agree that it's really disappointing that more tools aren't built to have a responsive canvas where you can play with sizing and set how the design responds. The answer I hear is to get to HTML prototypes as soon as possible, but it's not as fast to "sketch" in that medium (thus frameworks like bootstrap), so I think potential ideas are left unexplored.