I am going to share my experience, hopefully this will help someone: about 3 1/2 years ago, I went through a brief period of long hours at my desk (I had just previously had a hiking accident, dislocated shoulder, broke bones, and found that a period of long-hours and hard work took my mind off of recovering from shoulder surgery).
During this brief period I developed blood clots in one leg from sitting too long, and was really lucky to survive two large pulmonary embolisms. I often share this story as a warning to others. BTW, I average wilderness hiking for about ten hours a week (gentler walks when recovering from surgery) and that was not enough to prevent the blood clots.
Now, I use a 20 minute timer to get me up and walking around for a few minutes, 3 times an hour. Frequently standing and walking around is a recommended habit! Bad sitting habits almost killed me, and I needed over two years to mostly recover, so please take this seriously.