Cheers to the Wine dev team for all their hard work.
It's not just you. Even my professors think it's pretty cool that I can fire up Windows apps inside Linux while all of my terminals with their garish Vim syntax highlighting continue to stare at them :-)
Great project.
I also use it to play Dwarf Fortress. It, unfortunately, doesn't do very well with any of the other Win games that I occasionally play.
So, it's a problem, but it's not as big a problem as not being able to test quickly and easily on IE. IE is the bitch that never works right...at least Safari's deficiencies are relatively well understood and rarely hateful (they're usually just limitations and not-quite-there standards support, rather than horrifying rendering bugs that conflict dramatically with the standards).
Wine also supports OpenGL, so if your app (or game..) uses that, Wine easily beats any VM solution I've tried. It also implements part of Direct3D on top of OpenGL, but that's substantially slower. Still better than no D3D support as in most VM packages, of course.
Maybe it's time I installed wine.