It's going to be entirely different I feel. Instead of manipulating graphics on a flat screen, focus will probably be on manipulating physical objects on a table / in a room.
Watch his 2 talks that highlight the thinking and inspiration behind the RealTalk project:
https://www.youtube.com/watch?v=klTjiXjqHrQ https://www.youtube.com/watch?v=agOdP2Bmieg