As far as wikipedia is concerned, yes there are biological mental differences between men and women. I see a lot of "This is so disgusting I won't even respond to it," which is a cop-out.
But here's wikipedia:
https://en.wikipedia.org/wiki/Sex_differences_in_humans#Psyc...
We don't really know how much of a difference those biological differences make. There is a lot of research that show women (on AVERAGE) are more people oriented. But the percentage and distribution of women vs men that are thing vs people oriented isn't well settled. We have some data on outlooks in adults but that is obviously _not_ pre-culture.
When looking at [research on the matter](http://emilkirkegaard.dk/en/wp-content/uploads/Men-and-thing...):
Therefore, from the inter-individual perspective,the
individuals who pursue STEM careers are more likely to
be male than female. For example, assuming that
individuals within the highest 25% of a population
interest distribution are likely to make occupational
choices consistent with an interest type, the number of
women entering the engineering occupation, then, is only
19.5% of the number of men entering the field. This
percentage is very similar to the actual female–male
ratio of individuals employed in engineering. In science
and mathematics interest distributions, the female–male
ratios in the upper 25% asymptote are 0.60 and 0.64,
respectively. However, the actual female–male ratio of
individuals employed in the field of physical sciences
is only about 0.40 and, in mathematics, it is about
0.45. This discrepancy between interest data and real
employment composition indicates that there may be
reasons other than sex differences in interests that can
account for gender disparity in science and mathematics.