In other words, you can take out a large short position without needing any fulfillment while at the same time it factors as 'shares short' against Bitcoin. 'Shares short' is a major component used by institutions to calculate or re-price to the downside and when these numbers are inflated that can result in inaccurate pricing for the benefit of the manipulator.
There are plenty of examples of this and one of the most high profile cases is related to OSTK (Overstock): https://en.wikipedia.org/wiki/Patrick_M._Byrne#Campaign_agai...
It's a high-level form of manipulation. This will also reduce Bitcoins volatility and opportunity for large gains in short periods of time.
Of course the reverse is true if institutions want to battle it out on the short and long side but meanwhile the banking divisions of investment banks (JPMorgan et al) remain scared to death of Bitcoin. Ultimately, Bitcoin will have to have more institutional allies and supporters than the worlds banks (banks hate Bitcoin, it makes them irrelevant in the near future) which is quite possible.
New cryptos with low floats (low circulating supply) won't be affected as much thereby offering larger gains in shorter periods of time which will attract more of the typical cryptocurrency day traders and traditional traders.
More on this here: https://news.ycombinator.com/item?id=13844765