The good news is that we can get to even better results than Apple 2 by choosing pieces carefully. This is not my final result, but I'm seeing about 19ms from USB to light on a 2017 Macbook Pro 13" connected to a 144Hz monitor.
Given the unexpectedly large contribution of the keyboard, I think there is a _tremendous_ business opportunity in empirically validated actual low latency keyboards. Gamers will eat these up, but I would buy one in an instant for coding.