Oh yeah, 6th street - 8th street on market is still the same. I actually walked back from the Mission one night and one of my co-workers was like "You walked me through a crack den." Most of the people down there were strung out and not violent, but he was definitely not comfortable.
Gilde[1] is right near the area you're talking about and they provide tons of services for the homeless and mentally ill so there is a high concentration around that area.
[1] - https://www.glide.org