I use ~1200 tabs. I used to deal with Chrome stalling by periodically killing all Google Chrome Helper processes, and a few months ago switched to Firefox (less sluggish) from Chrome. Last week I decided to try Chrome again and was pleased to find that (with the same tab set) Chrome 71 is amazingly fast; new tabs open instantly, I can immediately enter a search query or URL, and the browser remains stable over time. Firefox, by contrast, is noticeably slow (but better than older Chrome) when opening new tabs or handling queries. So it's back to Chrome for me; it is now only slow when starting for the first time, when it processes the 1200 tabs for a few minutes.

(I do use The Great Discarder, but did so before switching to Firefox, too.)