Yes, but the effort to package the sort of software that's causing issues in python for the Guix/Nix/Spack/Easybuild class of systems is herculean[0] and idiosyncratic.
The groups maintaining and promulgating 'bad' packages would have to relinquish control over some of the dependencies they're currently venturing in or statically linking, or packagers have to reverse engineer their build systems, do that work themselves, and maintain it going forward.