In the social sciences, they call this 'belief perseverance'. To take this to an extreme, think of how many generations of people were convinced of geocentrism.
Were I in the position George found himself in, I would start by asking deeper questions about how the process works, how it fails, and how one can test that it is working as expected. If people get evasive it lends credence to the dissonant information, if they are forthcoming and have answers to the questions, it tends to support the core belief. "Trust but verify" is often used in this sort of context.
Always listen for meta-data and probe it when it throws up red flags. When someone gets angry in response to what seems like a simple question, follow that anger to see where it originates.
If their product had worked, after a few years the return on investment could have been substantial. It would have been significant loss pulling money out before release to mass market.
George Shultz is 98 years old. It's not like you can take your money to the grave. I would like to imagine he was doing all this for his family. I would also like to imagine that if you have a 9 billion dollar valuation company, and you bring together the right talent, Holmes could have somehow pulled off at least some value added breakthrough.
The real issue was when they started to lie and put people's safety at risk. But theranos had significant social proof. Whatever fraud or risks could have been brushed off as non systemic
I'm sure there will be many books and case studies on this as time passes and more facts are revealed. Tangible evidence (e.g., taped conversations) would be interesting. I'd want to hear what people like George Shultz were saying, and how they were reasoning these things in the timeline. I think this is a historic case worth learning from.
I see that a lot. People just want to believe, they want to follow, to find someone to show them the way. Shine a bright light in the darkness and people will flock to you and sit at your feet and follow in your footsteps even if you don't know where you're going. And you don't; you never do. Your little light can only cut the darkness so far ahead of you.
Sometimes you genuinely want to find a way, sometimes you're just shining a light to attract suckers, like an angler fish. But people will always come to you if you promise them all the answers- and often stick around long after they know you have nothing, because there's nothing left for them to do. They can check out, but they can never leave.
I wonder if it has something to do with being in a world (i.e., a "system") that people are still trying to understand? Over time, science tools like microscopes and telescopes have helped individuals shift their thoughts on the way the world works. I wonder what the next breakthrough tools will be to help us advance our grasp of the world?