Another fact about Bolivians ... they are, on average, the shortest people in the world.
https://www.worldatlas.com/articles/countries-with-the-short...
https://www.worldatlas.com/articles/countries-with-the-short...
I'm on my cellphone so I don't have the paper on hand, but there was a big study where they compared lung cancer rates in different geographic areas and found that the highest cancer incidence was at sea level, whereas the lowest was at higher elevations. They tried controlling for other obvious variables but elevation was unquestionably the best explanation.
Oxidation may explain plaque in arteries.