IMO uBlock Origin in Medium blocking mode is the best "less is more" setup.

[1]: "uBlock Origin in Medium mode for Lighter and Stronger Protection, with Less websites breakage and hassle"

https://malwaretips.com/threads/ublock0rigin-in-medium-mode-...

[2]: Blocking mode: medium mode

https://github.com/gorhill/uBlock/wiki/Blocking-mode:-medium...