Losing Twitter would be devastating, Venezuelans rely on Twitter to get their local news, it has effectively replaced traditional media as those have been taken over by the Government. People rely on networks of freelance journalists and smaller media companies to get what is happening locally. Losing Twitter would boost the Maduro regime.
Also, losing banking access (as it already happened with Transferwise) would plunge people further into poverty. A LOT of people rely on their friends and family abroad sending them money to survive, others work remotely for companies outside the country so they can earn in a foreign currency. A big part of the economy now functions via bank transfers abroad, you can literally buy in almost any shop now with a USD bank transfer. Losing that would wreck what's left of the economy.
Maduro must fall, but this will only empower him.