Jitsi wouldn't work for the Zoom meetings I admin. It's too technical for a very untechnical audience.
Zoom was hard enough, and 90% of the meetings in our ecosystem use Zoom, meaning they only need one app. Asking them to use Jitsi would require two (as every other meeting uses Zoom), which means a non technical audience has to learn 2 technical things instead of 1.
In the case of E2E encryption, every attendee has to type in the meeting key when they join for it to work. The users I work with will forget/won't understand why etc. They just want to speak to people. So that will render e2e useless if 1 out of 20 attendees doesn't do it.
Not to mention we have attendees who don't own a smartphone so have to dial in. Making the E2E Jitsi stuff pointless.
Jitsi is great for technical people. Zoom is great for non technical people.