The problem is that the scales involved are so ridiculously large that it could easily take 1 billion years to simulate one second. Even with 1 million years per second, simulation of a thousand years would require something like the age of the universe to compute. In that case, these "beings" could not be our descendants since they live in a universe with different laws.
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Actually, at a million years per second, the age of the universe (so far) would go by in five simulated hours. I don't want to speculate on how long we have until heat death, but I doubt it's long enough to simulate a single human lifespan at a million years per second.