Weird to be scrolling HN and see a link to my own book from years back; totally out of the blue with a different title. Thought someone had ripped off my title. Hmm... and a link I put up hours ago is first on the front page. Odd for sure
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Since you are here, what are your thoughts on how the United States could break its dependencies on big pharma? I found my own method that worked for me, but it won't work for most people.
Difficult question. As I document in the book, America has a long tradition of embracing synthetic ‘solutions’ to human problems, from barbiturates to Ritalin and Oxy. While at the same time demonising ‘natural’ substances. It’s a class based system of angels and demons
Agreed. Just about any time I bring up natural alternatives to RX I get drowned in echo chambers and broken records. I suspect money heavily influences that behavior.
The Rx system of synthetics has both sides happy: big pharma and the cartels
What degree of coverage to synthetics have? Meaning, what percentage of RX could they replace/deprecate? Is there a public database that has the formulas, processing and measuring methods?
I learned how to make Clonidine, but it's super dangerous if the measurements are wrong. One mistake and the nervous system shuts down.
The Rx industry knows if it can make it synthetically the rules totally change, as with the dangerously potent fentanyl. The head of NIDA showed in brain studies that cocaine and Ritalin were indistinguishable.
No synthetic cannabis, so it depends
> The head of NIDA showed in brain studies that cocaine and Ritalin were indistinguishable.
Am I missing something here? Should we be surprised that brain scans show that two CNS stimulants were indistinguishable?
Also, that study was conducted almost 30 years ago on mice [1].
I'm a firm believer in the saying, "the dose makes that poison." In this case, I'd also say the habits make the poison too. Even if the drugs have similar effects, I've never seen someone take bumps of Ritalin off the groove in keys, grow long pinky nails to take Ritalin, cook Ritalin in a spoon with a lighter to smoke it, have nose reconstruction surgery due to Ritalin abuse, etc. (I'm not saying abuse does not/can not happen). Can you name any songs about one's love/hate for Ritalin? While we are at it, I don't think Stephen King wrote, "Misery" about his struggles with Ritalin abuse either...
I just think using cocaine to damn Ritalin is such a glaring example of a false equivalence. The comparison does nothing, but further stigma people that need help for a legitimate disorder. Whether one believes the disorder has social or biological origins is irrelevant to people actually suffering.
Sure, we can all probably agree "Big Pharma" has done plenty of good and plenty of bad, but what are the other solutions? Outside of completely turning society upside-down, many people's only solution for help is "Big Pharma."
[1] Is methylphenidate like cocaine? Studies on their pharmacokinetics and distribution in human brain
https://www.researchgate.net/publication/15427108_Is_methylp...
From the link provided below, article by Volkow, re: cocaine and Ritalin in the brain (Eight healthy male subjects, 20 to 51 years of age):
For both drugs, their fast uptake in striatum paralleled the experience of the "high." For methylphenidate, the high decreased very rapidly despite significant binding of the drug in the brain. In contrast, for cocaine, the decline in the high paralleled its fast rate of clearance from the brain. We speculate that because the experience of the high is associated with the fast uptake of cocaine and methylphenidate in the brain, the slow clearance of methylphenidate from the brain may serve as a limiting factor in promoting its frequent self-administration.