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by Jimmc414·4y ago·view on hn ↗
To clarify this sequence has not been identified in any other virus in the wild. Additionally it codes for the section pertaining to the furin cleavage site which does not exist in any other observed beta coronavirus.
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That’s not correct, furin cleavage sites naturally occur in coronaviruses: https://www.sciencedirect.com/science/article/pii/S187350612...
You are correct. I should have stated furin cleavage sites have not been observed in another beta coronavirus. (Cold, MERS, SARS) I corrected my statement. Thank you for pointing that out.
That’s still incorrect. MERS is a Betacoronavirus and has a furin cleavage site: https://www.pnas.org/content/pnas/111/42/15214.full.pdf

Furin clevage sites haven’t been found elsewhere in SARS-Cov-2’s Sarbecovirus subgenus.

>To clarify this sequence has not been identified in any other virus in the wild.

>this sequence

>this

>sequence

Not with the same PRRAR sequence of amino acids, right?
Right, the furin cleavage site seems to have occurred independently in SARS-CoV-2 or one of its undiscovered close relatives.