It looks like this site fell out of use for a long time immediately after the Younger Dryas bolide strike of BCE 10,816 that wiped out the Clovis culture along with 30+ genera of large mammals, including horses, camels, giant sloths, dire wolves, and mammoths, and deposited a layer of sharply platinum-enriched dust and soot.
The proposal is that this impact triggered the Younger Dryas (YD) cooling and contributed to the end-Pleistocene megafaunal extinctions and human cultural changes. Equally, it should be clear that Firestone et al. (2007) are not claiming that the impact event itself wiped out many genera of megafauna or an entire human culture in an instant.
Of course, it's pretty obvious that the late quaternary extinction events weren't solely related to any particular impact event, if for no other reason than that many of the extinctions pre-date the impact and we can see the decline in North American megafaunal populations long before it.People used to say that about the K-T event, too. They later stopped saying it.
It is well established that and when the bolide strike occurred, coinciding with lots of interesting phenomena -- extinctions, climate hiccup, continent-spanning fires, platinum dust. Did it cause them all? That takes more work to establish. But we don't have any competing hypothesis.
https://sci-hub.se/10.1086/695703
A catastrophically big volcanic eruption in Europe only a century or two before the bolide strike seemed like it might have caused some things, but the timing does not now seem to match.
Something similar is true of the K-T boundary, except even overwhelmingly more-catastrophic eruptions blanketed India, and I don't think we know for sure which came first. It is just possible the bolide strike triggered the eruptions. (Certainly the eruption didn't cause the strike.)
[1] https://en.wikipedia.org/wiki/Quaternary_extinction_event
[2] https://static-content.springer.com/esm/art%3A10.1038%2Fs414...