Not sure about performance on an X220, but I've loved Fedora workstation edition. The default Gnome setup is pretty user-friendly in my opinion, a there's a decent amount of support to be found online.
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I'm not certain, but "needing a bash script to change the mouse scroll speed" sounds like the kind of inanity I've come to expect from Gnome. KDE is probably a better choice for somebody with this complaint.
It might also be a Wayland and/or libinput limitation.
I have used fedora on my x220 since I bought it new. Still runs perfectly.
HN would throttle my posting if I replied to everyone, so I'll just pick this comment, which speaks most directly to my experience, and thank everyone while thanking you. Do you remember if there were any tweaks you needed at the beginning, especially to get all the hardware working?