(based on my conversations with friends, family, and peers who started during and after the remote work boom, and my own experience switching from Eng to Product during the pandemic)

It depends on how your organization manages onboarding and communication. For a lot of junior emmployees, they don't get as much institutional support or ability to learn from watercooler conversations while being fully remote. When I started as a SWE, I was in the office and could pester experienced devs about this or that, and learn from conversations happening over lunch or over beers. While remote, that entire learning avenue shut down. In addition, most friendships are made thanks to the workplace. If you're fully remote, you aren't meeting other people and making friends. To some people that might be fine, but to others it's very restricting. That's a big reason why early-to-mid career (20-30) types prefer working in NYC over SF now - most other people our age are still there, while SF has become much older.