Slightly related: Does anyone else can't concentrate for long periods of time while sitting in front of a computer? I have mild scoliosis and a fear of varicocele (if that's relevant), and fortunately my work involves implementation of numerical algorithms/problem solving that I can first sketch on a notebook while laying on my bed and finally be coded sitting -on a rush-. Same with reading books. I'm thinking of purchasing a one-sided divan sofa and put it next to my desktop.
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A height adjustable desk is worth looking into if you don't already have one. Alternating between sitting and standing every 30-60 minutes is great for posture fatigue.
I have a similar mild scoliosis/desk avoidance thing. But what I've found is that it's not related to pain(I can game for hours and hours in a chair), it's more of a energy/bloodflow/breathing issue. Lying prone or supine is actually a good posture for relaxing enough to think carefully. Sitting upright induces attention and focus to immediate tasks but it can also produce woozy idis haze right after eating.
My favorite setup, overall, is floor sitting with a low desk. This lets the posture shift around moment-to-moment, including fully upright seiza type positions and supine or prone positions.
I’ve heard that some people even attempt to maximize walking time when important deadlines are close, because putting on serious faces and pretending to be productive at their desk is anecdotally so counterproductive to them. I think there are much to be discovered in where our creativity come from.