* A little scripting around opening the PR, which basically performs a "vimdiff <(git show baseref:file) file"-style dance on the changes(see :h diff). Using vim's tabs is great for this as they're really only views, so you can hold individual buffers open in distinct states at the same time.
* Scroll locking still works as expected in the main view, but you can avoid it in a separate tab when needed.
* [c and ]c move between hunks from the set of changes as they exist in the PR not in the working directory.
* dp and dg allow you to mark hunks as "done" by pushing/pulling the hunk in to the read-only diff buffer so that they're now hidden from the highlighted changes in the live buffer.
* Changes you make in the live buffer are available to commit directly, or push as a comment.
* All your regular editor things work as expected in the current state of the tree; go to definition, build integration, popup docs, etc.
Working like this means you're viewing changes against the PR's base, but have a clean working directory. That, to me, feels like a significant improvement over matklad's solution of having the working directory be in an unclean state to view the changes.
The environment I work in makes this behaviour super nice as changes will often be added with a --fixup commit, and then the tooling mangles them back together with a git-interpret-trailers call to attribute the fixup commit's author to the original commit at merge time. It also pulls text comments out of the PR and attaches a Reviewed-by trailer where appropriate, or the +1 equivalent to tack an Acked-by trailer on.