Out of all the games that would be closest to WFH, EVE Online takes the cake.
Most people who play the game seriously are part of a bigger organization, usually climbing the ladder by being trustworthy throughout the years. A lot of important things take place outside of the game itself, on Discord and sometimes even face to face.
The end game is basically you being able to effectively operate within an organization. I'd argue that's what most MMOs end game is at its core, but with EVE Online there's no sugar coating whatsoever.