As far as I know, Wolfram/Mathematica, LaTex, SymPy, Jupyter, Sage etc all rely on typewriter text for composing and inputting math. For this (and only this) reason, Maple is the only application that ever resonated with me, because input may be written in the same form it's written by hand, and it's baffling this capability isn't more commonplace. Is this a barrier to anyone else?
A very long time ago I used to play around with Derive5 in my youth. It was the most affordable Computer Algebra System (CAS) of the time and I learned to program in that funky one liner programming language where I had to strip all the white space from my editor and always be careful to balance parenthesis. I should dig up those old files and upload them to my github. I've been actually meaning to reimplement those operations in a more modern CAS system and see if I can more densely plot these curves I was studying with some iso-arc-length families of exponentials about the point (0,1).