If the dose is sufficiently large, possibly. In the doses commonly used in the Occident, not likely.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235659/ https://www.sciencedirect.com/science/article/abs/pii/S02546... https://www.thieme-connect.com/products/ejournals/abstract/1...

In Iran, pregnant women are advised to significantly reduce Saffron consumption. Note that the base level consumption is much higher in that country.