There is indoor lettuce I can buy at my supermarkets that is "zero pesticide" (you can just google it and find several, don't want to post any sort of links to products here).
I suspect it's hydroponic.
I suspect it's hydroponic.
It's axiomatically-speaking the one of the only few ways to make it happen.
"zero pesticides" implies no bugs/insects around to need spraying it in the first place, and doing that requires (A) a clean environment + (B) no regular soil (regular soil may have insect eggs / fungi in them).
The only things that come to mind are hydroponics & hydrogel agriculture.