If the file contains invalid JS (syntax error, or too new features for IE on Win7/8), or if it's >1MB (Chromium-based browsers & Electron limit), and the file is configured system-wide, then EVERY APP which uses wininet starts flooding the server with the requests over and over almost in an endless loop (missing/short error caching).
Over the years, this resulted in DDoSing my own server and blackholing its IP on BGP level (happened 10+ times), and after switching to public IPFS gateways to serve the files, Pinata IPFS gateway has blocked entire country, on IPFS.io gateway the files were in top #2 requests for weeks (impacting operational budget of the gateway).
All of the above happens with tight per-IP per-minute request limits and other measures to conserve the bandwidth. It's used by 500 000+ users daily. My web server is a $20/mo VPS with unmetered traffic, and thanks to this, I was never in the situation as the OP :)