The web development workflow is something that will be getting a lot of consideration in Lighttable - Chris Granger is the author of Noir which is the closest thing to a web 'framework' in the Clojure world.

Imagine you could create custom dashboards and debugging views for your domain types and your domain logic. Not just tailing the log and navigating some variables in a standard debugger.

I believe this will help immensely when approached from the right side, e.g. projects split into separate components with each having its own IDE setup (world, if you may) developed from the ground up together with the component itself.