Item — HN Reader

> For instance, mouse fathers exposed to nicotine(opens a new tab) sire male pups with livers that are good at disarming not just nicotine but cocaine and other toxins as well.

queue rationalist fathers microdosing nicotine patches before conception to give their kids the best chance at abusing drugs.

4 comments

What does disarming mean here?

I wound read it as “the drug has less effect” - so in that case you can better abuse these drugs if you are worse at “disarming” them I guess

"Hard headed", "not a cheap date", "not a lightweight"? Hard to say if increased tolerance is good or bad (especially if we're uncertain about how addictiveness/susceptibility to addictive behavior it passed)

I would have thought the main armament that nicotine has is its addictiveness

perhaps "making less harmful to the body"? this could potentially be accomplished separately from making them less effective

Damn. I didn't start substance abuse until after all my children were sired. Apparently I have done them an injustice by compromising their resistance to cocaine and other toxins. I have failed as a father!

Well, there's always next time.

ok now is my chance.

what is this (opens new tab) phenomenon?!

In the article, there's a link in the text right before they put that parenthetical. I'm guessing they're saying that the link interested them so they clicked it to read but opened it in a new tab so they could finish the current article first.

It seems to be hidden text in the page? Either way, it just shows up alongside links when you copy text from the article.

Oh interesting! That didn't even occur to me.

Probably a screen reader callout.

"microdose cocaine"

> rationalist

Not without a new cult spin-off you don't!