Not contradicting the second part, but I want to emphasise that they are different things. Slavery (and capitalism) can be extremely inefficient and simultaneously wildly profitable.
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Surely it's meaningless to compare the efficiency of slavery vs other systems, since your set of resources is completely different.
You could if you look at e.g. the crop yield (ceteris paribus). I don't know why you would, because what sane conclusion could you draw from it?
You could compare systems to identify which one produces the greatest profit from the least costs, which the main thing an entrepreneur cares about.