So they’ll be sued. The theories will be tested and we’ll see exactly where the line is (eventually). And probably somewhere uncomfortable, given SCOTUS.
There are legitimate ways agency political appointees can set funding priorities. Like this year we’ll focus on Alzheimer’s. But of course, we should take the least charitable reading of this - that it’ll likely be used for shenanigans. Punish enemies. Award cronies. Go after junk science, etc.