At the hosting level, the hosting you use will likely ban you for clearly illegal stuff. Same as blogspot dot com or Cloudflare could ban you for certain things.
At the application level, application admins/mods would moderate as any app does. This is similar to running any web service today with user generated content. It’s up to app developers to choose. Apps can also provide primitives for userland moderation, like Reddit does, or even ability to plug your own extra moderation services (which Bluesky allows). But again, this is largely how it works on any app with user-generated content.
There’s no “defederation” because there’s no analog of “community instances” that may fight with each other. There’s hosting, there’s apps, and there’s app-level moderation that works according to each app’s developer’s choices.
Does this help clarify it?