But yes, it absolutely makes more sense to run those plants 24/7 at 100% capacity.
And we have base-load that matches this reliable generating capacity very well.
The 40%-60% base load absolutely should be provided by nuclear if you don't have hydro (and even if you have hydro, some nuclear still makes sense).
The remainder should almost certainly be a mix: some more reliable nuclear, some storage, some wind, some solar.