Huge price difference in what you can do with buying a used 4U rackmount server and putting 3TB of RAM in it (64GB DIMMs x quantity 32 in a quad socket xeon, you can see some benchmark prices on eBay for sets of 16 or 32 matched 64GB ECC DIMMs) for <$30,000, vs the cost of trying to run it on real GPU hardware.
Now obviously, as of the time I write this, the full precision hasn't been released nor has anyone like unsloth run it through quantization yet to produce a "Q8" or "Q8-XL" variant of it. But I think it's going to need more than 1536GB of RAM, with a usable and large amount of context, more like 2TB and preferably 2.5 to 3TB.
I also predict that people who try to run it in Q4 and Q6 will get the worst of both worlds, less precision/lost knowledge but also not reliable output that comes out too slow. In my personal opinion if I'm going to deal with something that is smart but slow and running on limited budget hardware, I need it to be Q8.