Again, total prevention is a straw man. No-one is claiming that total prevention is an achievable goal. (Massive) reduction is.
I am a pilot. It is said the FARs (Federal Aviation Regulations) are written in blood. We still have fatal accidents from time to time, but they have been reduced by an almost incredible amount, especially considering how much air travel has increased.
Yeah, you could argue that the fundamental problem is that people want to travel and that the laws of physics are not favorable for the safety of air travel (gravity and all that). However, throwing your hands up in the air and saying we can't do anything without addressing the fundamentals is fundamentally and provably wrong.