A lot of things could be an existential threat, nuclear weapons, bio-weapons, climate change, the end of the Flynn effect, cratering birth rates, whatever.
You can always pick out a particularly dystopian vision of the future if you're so inclined. The doom narrative is sells ad revenue, so it's a huge amount of what we all consume online, but it's not really that mapped out to reality...
Somethings get worse, some things get better, in general, the average QoL for the average human is getting better. If we decide not to go to global thermonuclear war, or we decide to unplug any killer AIs that we invent, we'll probably be ok. If we can reduce the population to 3,000-ish humans after the Toba eruption, we can probably survive whatever self-imposed calamities we can create.
I think there's something particularly noxious about the present nihilism trend I see in a lot of this doom themed content. People should go outside and touch grass.
Things like climate change, psychometric test levels and birth rates change slowly and give us time to react, things like nuclear weapons are accessible to only a select number of actors, AI enabled bioweapons is neither of those.
(obviously "we" won't be around or whatever, but the point remains: yes, you should solve as many existential threats as you can before they're realized)
So is nuclear annihilation. Yet, here we are.
> "I occasionally think how quickly our differences worldwide would vanish if we were facing an alien threat from outside this world." -- Ronald Reagan at the United Nations [0]
We are going to be fine as long as we remember to be nice to each other, starting towards the people who are adjacent to us.
Her conclusion to the latter book comes out and says it, paraphrasing here:
> Nuclear war is terrifying in its destruction, but the chain of command limits the risk of a rogue actor. Whereas bio weapons can be designed and manufactured in relatively low tech environments with equal or greater magnitudes of impact.
Designing a modifcation to an existing virus is perhaps more achievable, but the implementation is still the hard part.
Thermo Fisher sells a kit to do this [1]. It's something you might do a few thousand times on the way to actually generating a novel virus.
> I’d argue estimate the risks of a synthetically induced pandemic of massive impact this century are very high
I'd argue that it probably already happened, and had nothing to do with AI.
[1] AAV transfection.
It'd be like releasing an invasive species into an ecosystem that has not co-evolved to co-exist with it.
I will kickstart a home DNA printer
I will name it Torment Nexus
I will be rich
Although, I must admit, as a doomer, I'm pleasantly surprised things aren't already worse than they are.
A profitable prediction markets trader who goes by the alias semiotic rivalry posted this prediction on his X account recently:
> Prediction: in 1-2 years, almost everyone will agree that open sourcing the best AIs is totally crazy as the AIs become capable of autonomous hacking of most humans and institutions, serious terrorism and creation of biological weapons, etc.
And I mostly agree with him. As much as it's awful to have such a concentration of capabilities in the hands of a few governments or corporations, as far as I can tell there are no easy answers here, only a matter of trade offs and different risks.
If the Manhattan project could build a fat man in 4 years your state university's physics department has somebody who could reproduce that given the necessary resources. It might take them longer than four years given that they are not staffed with the modern equivalents of Oppenheimer, teller, et al but they could do it within a human lifetime if they actually wanted to cause a mass-casualty event and weren't afraid of the aforementioned JDAM.
did you mean greater number of people with less resources?
EDIT: thanks to others that point out how you can interpret this differently, which I think is: "it is now easier for smaller teams with fewer resources" rather than my original interpretation of "power is now concentrated so that fewer people can do this than before"
However I think the result is disappointing, it concludes the only solution is a massive preventative surveillance state and global governance.
And technology doesn’t really care what you use it for. It can be constructive or destructive.
It “only” enhanced local destructive potential, until last century. Then it got to the point where a huge effort could produce a truly global catastrophe. And then a bit smaller effort. And technology continues to march on.
AI Just Created Viruses Not Found in Nature
https://news.ycombinator.com/item?id=49200213
Artificial Intelligence used to design new viruses
What we _can_ do is invest in detection, rapid response technology (vaccines etc), and attempt to mitigate and stratify the possibilities of this happening in the worse ways.
Today's knee jerk prohibitions, and fanciful notions of prohibition working are not facilitating those changes.
Edit: I'm a PhD biochemist that has done a fair bit of virus modification. Love the downvotes. Never change HN. ¯\_(ツ)_/¯