The danger is that (to quote Jurassic Park) "life always finds a way", and the risks are massive.
A good example of the risks of mirror chirality is thalidomide - thalidomide has two enantiomers (one that provides sedative and anti-nausea effects and another that causes the infamous thalidomide birth defects) which the human body naturally flip-flops when administered.
The risk to reward ratio is negatively misaligned (edited) when factoring the catastrophic risks and how easy it would be to weaponize (either on purpose or inadvertently).