Well, I use http://ink.sapo.pt (full disclosure: I work there.)
It's pretty complete and is constantly updated -- and besides including a battle-tested JS library of its own, it is evolving toward eschewing some of the "usual" dependencies.
One of the key reasons I use it outside work is that it targets _generic_ sites and can be customized and/or pulled in piecemeal if you take the time to build your own version.