He doesn't believe that the issue is at all that the low hanging fruit are gone.
"I would argue that there was never any low-hanging fruit; it was always of intermediate height and the question was, were people reaching for it or not" - Peter Thiel
http://www.technologyreview.com/qa/530901/technology-stalled...
Thiel is still very much worth reading though. FWIW, Tyler Cowen would say the same; "The Great Stagnation", his book before "Average is Over", is dedicated to Thiel.
if even the sentences happen to be the same, i prefer to listen to someone who has real world experience building companies vs just economists whose being wrong has no direct impact on themselves. skin in the game and all that.
First-hand accounts always run the risk of generalising the particular but academic accounts run the risk of being too general. In both cases the problem comes from falling in love with your own model and not paying enough attention to inconvenient data.
Now I think I'll go back and get it and give it a read.
Also, while we're talking books, I'll throw in a plug for The Origin of Wealth by Eric D. Beinhocker. It's a fascinating read for anybody interested in economics, capitalism, etc. It's not targeted at entrepreneurs per-se, but the principles in there have some interesting implications (if true).