Only you know the answer to this, so what do you think? Ask yourself, 1) if you worked less and made her happy or 2) your continued working at this pace and let her leave, what would you regret more in 5 years? Maybe you won't know how you really feel about her until you leave her. That's what happened with my wife and I.
I understand the draw of work. To this day I still work too much because I absolutely love what I do and the feeling it gives me. But I've been married 6 years and I love my wife more. If my work got in the way of our relationship, I would change things. But this is only because I know she's worth it.
So look over the advice here, but you're the only one that can really answer that question. The answer isn't at the end of some math equation, it's in your gut. Honestly, IMHO if you have to ask us just let her go and get back to work.