Ironically cullings where first aimed at stopping the "unsufferable increasing in the number of wolf damages" claimed by stockbreeders. The obtained was just the opposite. More damages by wolves and also by dogs.
Researchers showed later that in a lot of cases shepherd dogs, or just the harsh wheather where the real culprits, but, as the death by wolves where assisted by government and the death by a common disease or a blizzard where of course not paid, all deaths were charged to the scavenging wolves and paid by government.
http://m.rspb.royalsocietypublishing.org/content/282/1802/20...
Other things of interest is that we can actually see variance in behavoir increasing as human density increases. The error bars (standard deviation) on time spent at kill sites (or really doing anything) open right up the moment housing appears.
The truly destructive thing is roads and habitat pressure due to proximity of urban environments (noise, smells, food sources) that alter daily pattern. Large prey (deer, etc...) are creatures of habit driven by day/night patterns, wind, and their belief that everyone is out to get them. Seems to me They would be much more likely to alter their routine due to human pressure but the paper doesn't speak to that (if it does I missed it). And where the food goes, the predators go.
This is just my experience gained from being an avid outdoorsman for many years.