Adrenal insufficiency or Fatigue as they call it is a real problem from coffee OD though, Instead of caffeine i recommend Piracetam, far far lower LD50 score than caffeine and it's virtually impossible to OD or die from taking too much from this stuff.
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Indeed - it looks like the LD50 for Piracetam is about 15x that of caffeine in terms of mg/kg body mass.
http://www.sciencelab.com/msds.php?msdsId=9926585 - caffeine Toxicological Data on Ingredients: Piracetam: ORAL (LD50): Acute: 2000 mg/kg [Mouse].
http://www.sciencelab.com/msds.php?msdsId=9927475 - Piracetam Caffeine LD50 Acute: 192 mg/kg [Rat]. 127 mg/kg [Mouse]. 224 mg/kg [ Rabbit].
Presuming human equivalence to mice - A 185 pound person would need to ingest about 168 grams of piracetam as compared to around 10 grams of caffeine.
But - it's really important to note that both are toxic to the point of being fatal in easily digestible, relatively small amounts. Caffeine, in particular, can creep up on you pretty quickly - penguin mints are 1/2 gram per tin. (75 * 7 mg/mint).